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Briefings in Functional Genomics and Proteomics Advance Access published online on January 10, 2008
Briefings in Functional Genomics and Proteomics, doi:10.1093/bfgp/elm031
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© Oxford University Press, 2008, All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

The state of proteome profiling in the fungal genus Aspergillus

Yonghyun Kim, M. P. Nandakumar and Mark R. Marten

Corresponding author. Marten M.R, Department of Chemical and Biochemical Engineering, University of Maryland Baltimore County (UMBC), 1000 Hilltop Circle, Baltimore, MD 21250, USA. Tel: +1-410-455-3439; Fax: +1-410-455-1049; E-mail: marten{at}umbc.edu

Aspergilli are an important genus of filamentous fungi that contribute to a multibillion dollar industry. Since many fungal genome sequencing were recently completed, it would be advantageous to profile their proteome to better understand the fungal cell factory. Here, we review proteomic data generated for the Aspergilli in recent years. Thus far, a combined total of 28 cell surface, 102 secreted and 139 intracellular proteins have been identified based on 10 different studies on Aspergillus proteomics. A summary proteome map highlighting identified proteins in major metabolic pathway is presented.

Keywords: proteomics, Aspergillus, filamentous fungi, cell-surface proteins, secreted proteins, metabolic pathways


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