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Briefings in Functional Genomics and Proteomics Advance Access published online on October 29, 2007
Briefings in Functional Genomics and Proteomics, doi:10.1093/bfgp/elm026
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© Oxford University Press, 2007, All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

Development and perspectives of scientific services offered by genomic biological resource centres

Florian Wagner, Karsten R. Heidtke, Bernd Drescher and Uwe Radelof

Corresponding author. Uwe Radelof, ATLAS Biolabs GmbH, Friedrichstraße 147, 10117 Berlin, Germany. Tel: +49 (0)30 31 989 660; Fax: +49 (0)30 700 1431 226; E-mail: radelof{at}atlas-biolabs.de

A number of fundamental technical developments like the evolvement of oligonucleotide microarrays, new sequencing technologies and gene synthesis have considerably changed the character of genomic biological resource centres in recent years. While genomic biological resource centres traditionally served mainly as providers of sparsely characterized cDNA clones and clone sets, there is nowadays a clear tendency towards well-characterized, high-quality clones. In addition, major new service units like microarray services have developed, which are completely independent of clone collections, reflecting the co-evolution of data generation and technology development. The new technologies require an increasingly higher degree of specialization, data integration and quality standards. Altogether, these developments result in spin-offs of highly specialized biotech companies, some of which will take a prominent position in translational medicine.

Keywords: services, resource centre, microarrays, synthetic biology, translational medicine, functional genomics


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