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Briefings in Functional Genomics and Proteomics Advance Access published online on February 22, 2006
Briefings in Functional Genomics and Proteomics, doi:10.1093/bfgp/ell014
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© Oxford University Press, 2006, All rights reserved. For permissions please email: journals.permissions@oxfordjournals.org

Paper

Algorithmic approaches for identification of RNA editing sites

Erez Y. Levanon and Eli Eisenberg *

* To whom correspondence should be addressed.
Eli Eisenberg, E-mail: eli.eisenberg{at}gmail.com


  Abstract

Recently a number of groups have introduced computational methods for the detection of A-to-I RNA editing sites. These approaches have resulted in finding thousands of editing sites within the genomic repeats, as well as a few novel genetic recoding sites. We review these recent advancements, emphasizing the principles underlying the various methods used. Possible directions for extending these methods are discussed.

Keywords: RNA editing; genomic repeats; human-mouse comparison.

Erez levanon is a PhD student in the Sackler School of Medicine, Tel Aviv University (Tel Aviv, Israel) under the guidance of Prof. Gideon Rechavi. He also works as a research scientist in the biotechnology company Compugen Ltd.

Eli Eisenberg is a senior Lecturer in the School of Physics and Astronomy in Tel Aviv University. His interests include mesoscopic physics and statistical mechanics as well as bioinformatics.


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