Skip Navigation


Briefings in Functional Genomics and Proteomics Advance Access originally published online on March 12, 2007
Briefings in Functional Genomics and Proteomics 2007 6(1):59-69; doi:10.1093/bfgp/elm001
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
6/1/59    most recent
elm001v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Grant, K. J.
Right arrow Articles by Wu, C. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grant, K. J.
Right arrow Articles by Wu, C. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© Oxford University Press, 2007, All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

Advances in neuromembrane proteomics: efforts towards a comprehensive analysis of membrane proteins in the brain

Kathleen J. Grant and Christine C. Wu

Corresponding author. Christine C. Wu, Department of Pharmacology, University of Colorado School of Medicine, Fitzsimons RC1 South, L18-6117, P.O. Box 6511, Mail Stop 8303, Aurora CO 80045, USA. Tel: +1-303-724-3351; E-mail: christine.wu{at}uchsc.edu

Proteomic investigation of normal and diseased brain states has the potential to reveal novel molecular therapeutic and diagnostic targets for a multitude of pathological central nervous system conditions. Due to their unique properties, integral membrane proteins are likely to play a central role in the aetiology of these disorders. These properties, however, have prevented comprehensive analysis of this important class of proteins. Recent advances in sample preparation and proteomic quantification platforms, specifically focused on recovery and enrichment of integral membrane proteins, are discussed.

Keywords: membrane proteins, mass spectrometry, neuroproteomics, proteomics, brain, quantification, sample preparation


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.