Briefings in Functional Genomics and Proteomics Advance Access originally published online on February 22, 2006
Briefings in Functional Genomics and Proteomics 2006 5(1):43-45; doi:10.1093/bfgp/ell014
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special Issues Papers |
Algorithmic approaches for identification of RNA editing sites
Corresponding author. Eli Eisenberg, School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel. Tel: +972 3 640 7723; Fax: +972 3 640 2979. E-mail: eli.eisenberg{at}gmail.com
Recently a number of groups have introduced computational methods for the detection of A-to-I RNA editing sites. These approaches have resulted in finding thousands of editing sites within the genomic repeats, as well as a few novel genetic recoding sites. We review these recent advancements, emphasizing the principles underlying the various methods used. Possible directions for extending these methods are discussed.
Keywords: RNA editing, genomic repeats, human-mouse comparison