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Briefings in Functional Genomics Advance Access published online on September 19, 2008
Briefings in Functional Genomics, doi:10.1093/bfgp/eln042
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© The Author 2008. Published by Oxford University Press. For permissions, please email: journals.permissions@oxfordjournals.org

Technological developments in lipidomics

Weimin Hou *, Hu Zhou *, Fred Elisma *, Steffany A. L. Bennett and Daniel Figeys

Daniel Figeys, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5. Tel: +(613) 562 5800 ext 8674; Fax: +613-562-5655; E-mail: dfigeys{at}uottawa.ca.

Lipid analysis is a well-established field of research that focuses on one lipid or a few lipids. The recent developments in mass spectrometry technologies have enabled more comprehensive studies to be performed on lipids present in a sample. The move towards extensive lipid research has led to the coining of the term lipidomics, which is defined as the ensemble of lipids present in a sample. In this review, we will discuss the technical developments in the field of lipidomics and the current limitations of this nascent field.

Keywords: lipidomics, systems biology, mass spectrometry, HPLC, identification, quantitation

*These authors contributed equally to this work. Corresponding author


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