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Briefings in Functional Genomics and Proteomics Advance Access published online on October 17, 2007
Briefings in Functional Genomics and Proteomics, doi:10.1093/bfgp/elm027
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© Oxford University Press, 2007, All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

Resources, standards and tools for systems biology

Christoph Wierling, Ralf Herwig and Hans Lehrach

Corresponding author. Christoph Wierling, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany. Tel: +49 30 8413 1272; Fax: +49 30 8413 1380; E-mail: wierling{at}molgen.mpg.de

Modelling and simulation techniques are valuable tools for the understanding of complex biological systems. The design of a computer model necessarily has many diverse inputs, such as information on the model topology, reaction kinetics and experimental data, derived either from the literature, databases or direct experimental investigation. In this review, we describe different data resources, standards and modelling and simulation tools that are relevant to integrative systems biology.

Keywords: Bioinformatics, systems biology, pathway databases, systems biology standards, modelling and simulation, modelling tools


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