Skip Navigation


Briefings in Functional Genomics Advance Access originally published online on July 28, 2006
Briefings in Functional Genomics 2006 5(3):209-221; doi:10.1093/bfgp/ell028
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
5/3/209    most recent
ell028v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Verdone, L.
Right arrow Articles by Di Mauro, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Verdone, L.
Right arrow Articles by Di Mauro, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© Oxford University Press, 2006, All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

Special Issue Papers

Histone acetylation in gene regulation

Loredana Verdone, Eleonora Agricola, Micaela Caserta and Ernesto Di Mauro

Corresponding author. Ernesto Di Mauro, Dipartimento di Genetica e Biologia Molecolare, Università ‘La Sapienza’, P.le Aldo Moro 5, 00185, Rome, Italy. Tel: ++39–06–49912096; Fax: ++39–06–49912500; E-mail: ernesto.dimauro{at}uniroma1.it

Genetic information is packaged in the highly dynamic nucleoprotein structure called chromatin. Many biological processes are regulated via post-translational modifications of key proteins. Acetylation of lysine residues at the N-terminal histone tails is one of the most studied covalent modifications influencing gene regulation in eukaryotic cells.

This review focuses on the role of enzymes involved in controlling both histone and non-histone proteins acetylation levels in the cell, with particular emphasis on their effects on cancer.

Keywords: nucleosomes, gene expression, acetylation, deacetylation, cancer


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Genes & CancerHome page
G. Foltz, J.-G. Yoon, H. Lee, L. Ma, Q. Tian, L. Hood, and A. Madan
Epigenetic Regulation of Wnt Pathway Antagonists in Human Glioblastoma Multiforme
Genes & Cancer, January 1, 2010; 1(1): 81 - 90.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
H. Makkonen, M. Kauhanen, V. Paakinaho, T. Jaaskelainen, and J. J. Palvimo
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers
Nucleic Acids Res., July 1, 2009; 37(12): 4135 - 4148.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.